Previous Studies

Chronic Low Back Pain

BENEFIT– Prospective, multi-center, randomized, parallel assignment, single-blind, interventional feasibility study. Prospective Clinical Trial of Duty Cycled Stimulation Using the Senza™ Spinal Cord Stimulation (SCS) System: CA2015OUS DC.

Sacroiliac Joint Somatic Dysfunction

A Prospective, Multi-Center, Bi-Phasic Randomized Design to Compare Outcomes of the CornerLoc™ SI Joint Stabilization System and Intra-Articular Sacroiliac Joint Steroid Injection in Patients with Refractory Sacroiliac Joint Dysfunction

Moderate to severe acute lower back pain

A Phase 2, Randomized, Double-blind, Placebo-controlled, Parallel Group, Multicenter Study to Evaluate the Safety and Efficacy of SP-103 in Subjects with Moderate to Severe Acute Lower Back Pain

Intractable chronic back pain

Open-Label, Post Market Study: A Clinical Trial to Study the Effects of DTM Spinal Cord Stimulation (DTM™SCS) programs in treating Intractable Chronic Back Pain in Subjects without prior history of Spine Surgery

Intractable Chronic Upper Limb Pain

A Post-Market, Observational Clinical Study to Evaluate the Effects of DTMTM SCS programming in treating Intractable Chronic Upper Extremity Limb Pain

Chronic Abdominal Pain

SENZA-CAP – A Prospective Clinical Trial to Assess the Feasibility of the SenzaTM Spinal Cord Stimulation (SCS) System in the Treatment of Chronic Abdominal Pain.

Neurostimulation therapy for pain

RELIEF – A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain.

Lumbar spinal stenosis

Postmarket Registry for Evaluation of the Superion® Spacer.

Osteoarthritis of the knee

A randomized, double-blind, placebo-controlled, Phase III trial to evaluate the efficacy and safety of a single intra-articular injection of RTX-GRT7039 in adult subjects with pain associated with osteoarthritis of the knee

Episodic migraine

A Phase 3, Multicenter, Randomized, Open-Label Study to Evaluate the Long-Term Safety and Tolerability Of Oral Atogepant For the Prevention Of Migraine In Participants With Episodic Migraine

Differential Target Multiplexed Spinal Cord Stimulation - Chronic pain

The UPGRADE Study: Real World Outcomes® of Differential Target Multiplexed (DTM-SCS®) Stimulation in Existing and New Medtronic Intellis™ Implants 

Neurostimulation System - Chronic, intractable pain

Spinal Cord Stimulation in the treatment of Chronic, Intractable Pain using the Nalu™ Neurostimulation System (nPower™-US)  

Peripheral Nerve Stimulation - Knee replacement

Treatment of Post-Operative Pain Following Orthopedic Surgery with SPRINT® Peripheral Nerve Stimulation (PNS) System in a Randomized, Double-Blinded, Placebo-Controlled Study.

Opioid Withdrawal (Disorder)

A Randomized, Double-blind, Placebo-Controlled, Pilot Study to Evaluate the Safety and Effectiveness of LUCEMYRA in the Treatment of Opioid Withdrawal During an Opioid Taper in Subjects with Chronic Non-Cancer Pain

Lumbar disc herniation

A Multicenter, Randomized, Double-blind, Sham Controlled, Comparative Study of SI-6603 in Subjects with Lumbar Disc Herniation (Phase 3)

Acute treatment of migraine

AXS-07-301: MOMENTUM (Maximizing Outcomes in Treating Acute Migraine): A Randomized, Double-blind, Single-dose, Placebo-controlled Study to Assess the Efficacy and Safety of AXS-07 (meloxicam and rizatriptan) for the Acute Treatment of Migraine in Adults with Inadequate Response to Prior Acute Treatments

Back and Leg Pain from Sciatica

Primary objective:

  • Study the efficacy and safety of a lumbar injection in the treatment of pain associated with back and leg pain
  • 7 in person and 6 phone visits
  • Course of 12 months
  • Up to $1,530 ($120 for each in-person visit) in compensation
  • Male/Female

Pain Associated with Lumbosacral Radiculopathy

A Prospective, Multicenter, Randomized, Double-Blinded, Sham-Controlled Study to Evaluate the Efficacy and Safety of Clonidine Micropellets for the treatment of Pain Associated with Lumbosacral Radiculopathy in Adults: RePRIEVE-CM (achieving Radicular Pain Relief Via Epidural injection of Clonidine Micropellets). STX-015-18-01.

A Multicenter, Randomized, Follow-up Study to Evaluate the Long-Term Safety of Clonidine Micropellets for the Treatment of Pain Associated with Lumbosacral Radiculopathy in Adults: RePRIEVE-CM-LT (achieving Radicular Pain RelIEf Via Epidural injection of Clonidine Micropellets Long-Term) STX-015-18-02

Chronic Low Back Pain

BENEFIT– Prospective, multi-center, randomized, parallel assignment, single-blind, interventional feasibility study. Prospective Clinical Trial of Duty Cycled Stimulation Using the Senza™ Spinal Cord Stimulation (SCS) System: CA2015OUS DC.

Moderate to severe acute lower back pain

A Phase 2, Randomized, Double-blind, Placebo-controlled, Parallel Group, Multicenter Study to Evaluate the Safety and Efficacy of SP-103 in Subjects with Moderate to Severe Acute Lower Back Pain

Intractable Chronic Upper Limb Pain

A Post-Market, Observational Clinical Study to Evaluate the Effects of DTMTM SCS programming in treating Intractable Chronic Upper Extremity Limb Pain

Neurostimulation therapy for pain

RELIEF – A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain.

Osteoarthritis of the knee

A randomized, double-blind, placebo-controlled, Phase III trial to evaluate the efficacy and safety of a single intra-articular injection of RTX-GRT7039 in adult subjects with pain associated with osteoarthritis of the knee

Differential Target Multiplexed Spinal Cord Stimulation - Chronic pain

The UPGRADE Study: Real World Outcomes® of Differential Target Multiplexed (DTM-SCS®) Stimulation in Existing and New Medtronic Intellis™ Implants 

Peripheral Nerve Stimulation - Knee replacement

Treatment of Post-Operative Pain Following Orthopedic Surgery with SPRINT® Peripheral Nerve Stimulation (PNS) System in a Randomized, Double-Blinded, Placebo-Controlled Study.

Lumbar disc herniation

A Multicenter, Randomized, Double-blind, Sham Controlled, Comparative Study of SI-6603 in Subjects with Lumbar Disc Herniation (Phase 3)

Acute treatment of migraine

AXS-07-301: MOMENTUM (Maximizing Outcomes in Treating Acute Migraine): A Randomized, Double-blind, Single-dose, Placebo-controlled Study to Assess the Efficacy and Safety of AXS-07 (meloxicam and rizatriptan) for the Acute Treatment of Migraine in Adults with Inadequate Response to Prior Acute Treatments

Sacroiliac Joint Somatic Dysfunction

A Prospective, Multi-Center, Bi-Phasic Randomized Design to Compare Outcomes of the CornerLoc™ SI Joint Stabilization System and Intra-Articular Sacroiliac Joint Steroid Injection in Patients with Refractory Sacroiliac Joint Dysfunction

Intractable chronic back pain

Open-Label, Post Market Study: A Clinical Trial to Study the Effects of DTM Spinal Cord Stimulation (DTM™SCS) programs in treating Intractable Chronic Back Pain in Subjects without prior history of Spine Surgery

Chronic Abdominal Pain

SENZA-CAP – A Prospective Clinical Trial to Assess the Feasibility of the SenzaTM Spinal Cord Stimulation (SCS) System in the Treatment of Chronic Abdominal Pain.

Lumbar spinal stenosis

Postmarket Registry for Evaluation of the Superion® Spacer.

Episodic migraine

A Phase 3, Multicenter, Randomized, Open-Label Study to Evaluate the Long-Term Safety and Tolerability Of Oral Atogepant For the Prevention Of Migraine In Participants With Episodic Migraine

Neurostimulation System - Chronic, intractable pain

Spinal Cord Stimulation in the treatment of Chronic, Intractable Pain using the Nalu™ Neurostimulation System (nPower™-US)  

Opioid Withdrawal (Disorder)

A Randomized, Double-blind, Placebo-Controlled, Pilot Study to Evaluate the Safety and Effectiveness of LUCEMYRA in the Treatment of Opioid Withdrawal During an Opioid Taper in Subjects with Chronic Non-Cancer Pain

Pain Associated with Lumbosacral Radiculopathy

A Prospective, Multicenter, Randomized, Double-Blinded, Sham-Controlled Study to Evaluate the Efficacy and Safety of Clonidine Micropellets for the treatment of Pain Associated with Lumbosacral Radiculopathy in Adults: RePRIEVE-CM (achieving Radicular Pain Relief Via Epidural injection of Clonidine Micropellets). STX-015-18-01.

A Multicenter, Randomized, Follow-up Study to Evaluate the Long-Term Safety of Clonidine Micropellets for the Treatment of Pain Associated with Lumbosacral Radiculopathy in Adults: RePRIEVE-CM-LT (achieving Radicular Pain RelIEf Via Epidural injection of Clonidine Micropellets Long-Term) STX-015-18-02

Chronic Low Back Pain

Neurostimulation for pain

Chronic Abdominal Pain

Moderate Degenerative Lumbar Spinal Stenosis

Pain Associated with Lumbosacral Radiculopathy

Advanced Sumplemental Discogenic Pain

Intractable Chronic Upper Limb Pain

Chronic Low Back Pain

Neurostimulation for pain

Chronic Abdominal Pain

Moderate Degenerative Lumbar Spinal Stenosis

Pain Associated with Lumbosacral Radiculopathy

Advanced Sumplemental Discogenic Pain

Intractable Chronic Upper Limb Pain

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