Ongoing clinical Trials

New studies coming soon — please check back later for updates.

Neuropathic Pain

Chronic Nerve Pain in specific Area

(Chronic Focal Neuropathic Pain)

This study is evaluating a device-based treatment for adults with chronic, difficult-to-treat pain in the back, trunk, or limbs. The goal is to better understand how this therapy may help reduce pain and improve daily functioning.

Participants who are already planning to undergo this treatment as part of their care will be followed over time. This includes clinic visits at the start of treatment and follow-ups at approximately 3, 6, and 12 months. 

At these visits, participants may:

  • Complete questionnaires about pain and quality of life
  • Have their treatment settings reviewed
  • Provide feedback on symptom changes

You may qualify if you:

  • Are 18 years of age or older
  • Have chronic pain in the back, trunk, or limbs that has not improved with prior treatments
  • Are being considered for this type of device-based therapy as part of your care

You may not qualify if you:

  • Have certain neurological or medical conditions that increase risk
  • Have an active infection
  • Are pregnant
  • Have certain implanted devices or conditions that may interfere with the study

Neck Pain and Headache

This study is evaluating a minimally invasive treatment for adults with chronic neck pain and cervicogenic headaches that have not improved with conservative treatments. The goal is to better understand long-term pain relief and improvements in daily function after treatment.

Participants who qualify for the procedure will undergo a treatment designed to target nerves associated with chronic neck pain and headache symptoms.

Participants will be followed over time with visits at approximately:

  • 1 month
  • 3 months
  • 6 months
  • 12 months

At these visits, participants may:

  • Complete questionnaires about pain and quality of life
  • Discuss symptom improvement with the study team
  • Review medication use and daily functioning

You may qualify if you:

  • Are 18 years or older
  • Have chronic neck pain and headaches lasting at least 6 months
  • Have not improved with prior treatments such as medications, physical therapy, or other conservative care
  • Previously experienced temporary relief from diagnostic nerve block procedures

You may not qualify if you:

  • Are pregnant
  • Have certain bleeding disorders or require long-term blood thinners
  • Have uncontrolled psychiatric conditions
  • Have had certain prior neck surgeries

Diabetic Peripheral Neuropathy of the Feet

This study is evaluating a treatment patch for adults with painful diabetic nerve pain in the feet. The goal is to better understand how this treatment may improve pain and quality of life over time.

Participants who are newly prescribed this treatment as part of their care will receive the treatment patch and attend scheduled follow-up visits over several months (conducted over the phone).

At these visits, participants may:

  • Complete questionnaires about pain and daily activities
  • Discuss symptom changes with the study team
  • Have the treatment area evaluated

You may qualify if you:

  • Are 18 years or older
  • Have diabetic nerve pain in the feet
  • Have moderate to severe foot pain symptoms
  • Are newly starting this treatment patch

You may not qualify if you:

  • Have active foot ulcers or skin infections
  • Have certain skin conditions affecting the treatment area
  • Have previously been treated with this type of high-dose pain patch
  • Use very high doses of opioid pain medication

Chronic Low Back Pain Study

(Minimally Invasive Treatment Option)

This study is evaluating a minimally invasive treatment for adults with chronic low back pain caused by disc degeneration. The goal is to see whether this approach can safely reduce pain and improve daily function compared to standard non-surgical care.

Participants will receive either the study treatment or continue with standard non-surgical care. 

Those receiving the study treatment will undergo a minimally invasive procedure using a needle-based approach (no major surgery).

All participants will be followed over time, with visits at approximately:

  • 1 month
  • 3 months
  • 6 months
  • 12 months
  • 24 months

At these visits, participants will:

  • Complete questionnaires about pain and daily activities
  • Be evaluated for symptom changes and overall health

You may qualify if you:

  • Are between 22 and 85 years old
  • Have chronic low back pain lasting at least 6 months
  • Have not improved after standard treatments (such as physical therapy, medications, or injections)
  • Have pain primarily coming from one or two discs in the lower back

You may not qualify if you:

  • Have had prior back surgery
  • Have significant nerve-related leg pain (sciatica more than back pain)
  • Have certain spine conditions (such as severe spinal instability or fractures)
  • Have active infection or certain serious medical conditions
  • Are pregnant

Lumbar Spinal Stenosis Study

Pain, Numbness, and/or Cramping in the Legs

Key Inclusion Criteria:

  • Compile long-term outcomes of an implanted device in routine clinical practice
  • 9 in person visits
  • Course of 5 Years

Back and Leg Pain from Sciatica

Primary objective:

  • Study the efficacy and safety of a lumbar injection in the treatment of pain associated with back and leg pain
  • 7 in person and 6 phone visits
  • Course of 12 months

Peripheral Neuropathy

Primary objective:

  • Assess the efficacy and safety of a topical cream in cancer survivor adult patients with Chemotherapy-induced peripheral neuropathy (CIPN)
  • 4 in person visits
  • Course of 13 weeks

Pain, Numbness, and/or Cramping in the Legs

Primary objective:

  • Compile long-term outcomes of an implanted device in routine clinical practice
  • 7 in person visits
  • Course of 5 Years

Neuropathic Pain

Chronic Nerve Pain in specific Area

(Chronic Focal Neuropathic Pain)

Key Inclusion Criteria:

  • Are 18 years of age or older
  • Have chronic pain in the back, trunk, or limbs that has not improved with prior treatments
  • Are being considered for this type of device-based therapy as part of your care

Neck Pain and Headache

Key Inclusion Criteria:

  • Are 18 years or older
  • Have chronic neck pain and headaches lasting at least 6 months
  • Have not improved with prior treatments such as medications, physical therapy, or other conservative care
  • Previously experienced temporary relief from diagnostic nerve block procedures

Diabetic Peripheral Neuropathy of the Feet

Key Inclusion Criteria

  • Are 18 years or older
  • Have diabetic nerve pain in the feet
  • Have moderate to severe foot pain symptoms
  • Are newly starting this treatment patch

Lumbar Spinal Stenosis Study

Pain, Numbness, and/or Cramping in the Legs

Key Inclusion Criteria:

  • Compile long-term outcomes of an implanted device in routine clinical practice
  • 9 in person visits
  • Course of 5 Years

Chronic Low Back Pain Study

(Minimally Invasive Treatment Option)

Key Inclusion Criteria:

  • Are between 22 and 85 years old
  • Have chronic low back pain lasting at least 6 months
  • Have not improved after standard treatments (such as physical therapy, medications, or injections)
  • Have pain primarily coming from one or two discs in the lower back

Neck Pain and Headache

Key Inclusion Criteria:

  • Investigate the impact radiofrequency ablation on cervicogenic headache and neck pain 
  • 4 phone calls
  • Course of 1 year

Post Surgical Neuropathic Pain

Key Inclusion Criteria:

  • Has lasted pain for at least 6 months
  • Improve the quality of life for individuals who suffer from this condition.

Diabetic Peripheral Neuropathy of the Feet

Key Inclusion Criteria:

  • Do not have any current foot ulcers, skin inflammation, infection, redness, swelling, or gangrene
  • Do not have hypersensitivity to capsaicin

Neck Pain and Headache

Primary objective:

  • Investigate the impact radiofrequency ablation on cervicogenic headache and neck pain 
  • 4 phone calls
  • Course of 1 year

Diabetic Peripheral Neuropathy of the Feet

Primary objective:

  • Do not have any current foot ulcers, skin inflammation, infection, redness, swelling, or gangrene
  • Do not have hypersensitivity to capsaicin

Peripheral Neuropathy

Primary objective:

  • Assess the efficacy and safety of a topical cream in cancer survivor adult patients with Chemotherapy-induced peripheral neuropathy (CIPN)
  • 7 visits and up to 19 weeks

Upcoming Studies

Upcoming CRPS Study

We will soon be enrolling adults with Complex Regional Pain Syndrome (CRPS-1) in a clinical research study evaluating a potential treatment option aimed at reducing pain and improving symptoms in affected limbs. 

 

The study is intended for individuals with relatively recent CRPS symptoms and ongoing moderate to severe pain. 

Upcoming Sciatica Pain Study

We will soon be enrolling adults with moderate to severe lumbar radicular pain (sciatica-related leg pain) in a clinical research study evaluating an investigational injection treatment option.

Participants may undergo screening, imaging, pain assessments, and follow-up visits over multiple treatment periods. Some participants may qualify for an additional injection phase during the study.

Additional Information

Participation is voluntary, and all study procedures will be explained before enrollment.

Interested?

Contact our research team to learn more and see if you may be eligible. 

Study for individuals that have peripheral neuropathy as a result of chemotherapy

  • Primary objective: Assess the efficacy and safety of a topical cream in cancer survivor adult patients with CIPN
  • 4 in person visits over the course of 13 weeks, $480.00 in compensation
  • Onset of pain in hands or feet after prior treatment of cancer with taxanes or platins 
  • Painful symptoms can be accompanied by non painful symptoms (tingling/pins and needles, numbness)
  • Stopped chemotherapy treatment for at least 24 weeks 
  • Peripheral neuropathy pain for at least 24 weeks

Study for individuals that suffer from pain, numbness, and/or cramping in the legs

  • Primary objective: compile long-term outcomes of an implanted device in routine clinical practice 
  • 7 in person visits over the course of 5 years, $1,500.00 in compensation
  • Diagnosed with moderate degenerative lumbar spinal stenosis
  • Peristent leg/buttock/ groin pain, with or without back pain that is consistenly relieved by flexion actives (such as sitting or bending over a shopping cart)
  • That are able to sit for 50 minutes without pain and to walk for 50 feet or more
  • That have NOT had surgery of the lumbar spine
  • 45 years or older

Study for individuals that have significant pain due to diabetic peripheral neuropathy of the feet

  • Do not have any current foot ulcers, skin inflammation, infection, redness, swelling, or gangrene
  • Do not have hypersensitivity to capsaicin

Study for individuals that have chronic moderate to severe post surgical neuropathic pain

  • Has lasted for at least 6 months
 

Study for individuals that suffer from neck pain and headache

  • Has lasted neck pain and headache more than 6 months
  • Has not responded to other treatments (such as physical therapy, chiropractic care, bed rest, etc.)
 

Study for individuals with lumbar and/or lumbosacral radiculopathy

  • Primary objective: study the efficacy and safety of a lumbar injection in the treatment of pain associated with lumbar radiculopathy
  • 7 in person and 6 phone visits over the course of 12 months, $1,530.00 in compensation
  • Pain must have radicular component that have been present for at least 8 weeks, but not longer than 9 months
  • Insufficient pain relief or improvement following at least 8 weeks of:
    1. Non-pharmacological/ mechanical treatment (physical therapy, exercise, chiropractic treatment, etc.)
    2. Over-the-counter analgesics (non-steroidal anti-inflammatories, topical gels, creams or ointments
  • Has NOT had lumbar surgery and/ or intradiscal interventions

Study for individuals with osteoarthritis of the knee

  • Diagnosed with osteoarthritis of the knee
  • Pain in index knee has been present for at least 6 months
  • Insufficient pain relief with standard of care:-
    1. Non-pharmacological treatment (physical therapy, exercise, muscle strengthening, etc.)
    2. 1 or more courses of oral non-steroidal anti inflammatory drugs
    3. where appropriate, opioids, steroid injections
  • Have NOT had joint replacement surgery of the index knee
  • Have NOT had a history of significant trauma or surgery to index knee in past year
About Trials

What is a Clincial Trial?

Clinical trials are research studies performed in people that are aimed at evaluating a medical, surgical, or behavioral intervention. They are the primary way that researchers find out if a new treatment, like a new drug or diet or medical device (for example, a pacemaker) is safe and effective in people. Often a clinical trial is used to learn if a new treatment is more effective and/or has less harmful side effects than the standard treatment.

Why Choose Us

Mission and Strategy

Our strategy is to exceed study enrollment timelines and expectations, recruit the right patients, expedite contract and budget negotiations, and central IRB submissions. 

Our mission is to continually execute trial activities from initiation to completion and maintain loyalty to our Sponsors and CROs by delivering quality data. Our private practice, Kansas Pain Management (KSPM) works in collaboration with NRC to support this mission. Research team roles and responsibilities are well-defined and delegated in accordance by site standard operating procedures.

Contact us

Call us at

Amy (913)-825-2314 , Neda (913)-825-2315
We love our patients, so feel free to call during normal business hours and ask about current trials.

Location

Overland Park, Kansas - (Kansas City area)
Monday - Friday 8 am to 5 pm CST

Interested in a Clinical Research Study?

Complete the form below and a member of our research team will contact you to discuss eligibility and participation opportunities.

    Which study are you interested in?
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    Contact us

    (913)-825-2314
    (913)-825-2315
    We love our patients, so feel free to call during normal business hours and ask about current trials.

    Location

    Overland Park, Kansas - (Kansas City area)

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      Which study are you interested in?
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